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Laboratory of Molecular Image on Translational Research

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111週年校慶講座 許斐婷:勇於試錯,為未來精準定位做準備 ​

111 週年校慶講座壓軸,生命科學系許斐婷副教授以「放射背景起點,腦癌治療之路研究與成長分享」談一路走來的心路歷程。她不談高深莫測的學術議題,而是將自己跌跌撞撞的過程,最終在生醫領域發光發熱的試錯經驗坦然揭開,給予現場大學生具體的行動指南。

實踐排除法:在跌撞中收斂出最真實的自己

許斐婷最後幽默地分享,真正熱衷的事情甚至能讓一個人的性格在「J(計畫型)」與「P(彈性探索型)」之間流轉。從習慣井井有條,到學會接受實驗無法預期的失敗,這本身就是一場認知的翻轉。

「排除錯誤的選項,剩下就是你該待的地方。」許斐婷期望同學能保持好奇心並訂下不同的計畫、勇敢執行,長期下來的收斂將逐漸聚焦熱忱核心。她認為,在當前科技迭代極快、資訊碎片化的洪流中,大學生更需為自己建構深層思考與紮實知識庫的『護城河』。正如她的故事與研究經驗所證明──人生的軌跡從來不是一條拉直的線,真實的世界總是曲折向前的。

research resources

Main resources and equipment in LMITR

Our lab equip with following equipment including luminescence fluorescent imaging system (SpectraMax iD3), mouse surgical microscope platform and system, biomedical image analysis software (PMOD), luminescence imaging system (UVP ChemiDoc-It imaging system), Flow Cytometry (ACEA biosciences. Inc. NOVOCYTE), tissue homogenization system (gentleMACS™ Dissociator)... etc. The above-mentioned equipment can be used for the application of nanomaterials in cancer treatment and biomedical imaging.

Cooperators:

  1. Center for Advance Molecular Imaging and Translation, Chang Gung Memoiral Hospital, New Taipei City

  2. China Medical University Hospital, Taichung

  3. Institute of Nuclear Energy Research, Atomic Energy Council, Taoyuan City

  4. Taipei Medical University, Taipei

  5. National Cheng Kung University, Tainan

  6. National Yang Ming Chiao Tung University, Taipei

  7. The University of Melbourne, Australia

  8. Centre For Eye Research Australia

  9. New York University, USA 

 

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research projects

Gene Modified Mesenchymal Stem Cell Therapy and Diagnosis

Due to the characteristic of WJ-MSCs, we hypothesis that WJ-MSCs can be a cell carrier to delivery multi-targeted vectors which may markedly enhance the therapeutic efficacy of glioblastoma.

 

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Molecular Image Application on Cancer

1. Bioluminescence Imaging

2. Micro Positron Emission Tomography

3. MR Chemical Exchange Saturation Transfer

 

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4. Magnetic resonance imaging (MRI)

 

Theranostic 

1. Molecular Magnetic Resonance Imaging (mMRI)

    (Superparamagnetic iron oxide based MRI contrast agents)

2. Drug delivery efficacy (covert by MR signal intensity)

 

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Molecular Image Application on Immunology

Anti-bodies based immunotherapy 

Bioluminescence Imaging​​​​

(Luminescence-based reporter gene model )

 

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1. Low dose chemo combined adoptive T transfer

2. Antibody combination treatment

 

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